What is THC-P?
– THC-P is a new version of marijuana that is stronger and more potent than traditional THC.
– It is a synthetic cannabinoid that binds to the body's cannabinoid receptors, producing intense psychoactive effects.
– THC-P is believed to be up to 30 times more potent than regular THC.
How does THC-P differ from regular THC?
– THC-P has a longer-lasting and more intense high compared to regular THC.
– It is also believed to have a different chemical structure and mechanism of action in the body.
– THC-P may have potential medical applications, but more research is needed to fully understand its effects.
What are the potential risks and benefits of THC-P?
– The potential risks of THC-P include increased risk of addiction, impaired cognitive function, and negative mental health effects.
– On the other hand, THC-P may have potential benefits in certain medical conditions, such as chronic pain, nausea, and appetite stimulation.
– However, due to its potency and limited research, it is important to proceed with caution when it comes to THC-P use.
What Is THC-P?
THC-P or 8-tetrahydrocannabiphorol is a newly discovered cannabinoid that is hallucinogenic, meaning it can alter brain function and cause hallucinations or sensory distortions.
It was first identified in 2019 when European regulators issued a licensing agreement for the pioneer cannabis cultivar, called The Original Frontier, which allowed businesses to grow the hemp variety and sell derived goods.
According to the European Industrial Hemp Association (EIHA), it is a synthetic mixture of Multiple Cannabinoid Alcohol (F4, F2, and F1) and F3:CCC.
It is not a natural cannabinoid found in the marijuana plant, various parts of the cannabis plant, or cannabis products.
According to FDA research, THC-P is an agonist, or a chemical, that binds to CB1 receptors in the endocannabinoid system (ECS), which reacts to endogenous cannabinoids, like anandamide.
A preprint study dated May 2022 found evidence that THC-P and THC can help lessen peritoneal mesothelioma (cm) inflammation. It might further support its therapeutic capabilities.
Below is a list of various synthetic cannabinoids and their chemical structures.
Discovery of THC-P
There is a citation from the U.S. Patent No 17,067,341-B2, explained in WIPO/FEDER Patent Application Publication, PCT/CA2021/050277 published in 2021 that described the processes involved in producing the 6a,10a-dimethyl-delta-8-tetrahydrocannabinoid tetrahydrocannabiphorol (THC-P).
This unknown compound made them more relevant than ever in a rapidly changing cannabinoid landscape. Their particular growing and multilevel extraction optimization techniques required time and expertise.
Often mentioned in a text published in 2022 discussing drug delivery among others on International Journal of Drug Delivery Technology includes THC-P as a synthetic cannabinoid.
Through technical structuring, this alternative controlled substance can be potentially more potent than its natural counterparts as its construction is made synthetically.
Scientific Studies on THC-P Effects
Several scientific studies provide limited information about the effects that THC-P may have on the body when consumed.
New Version Marijuana
A single study only mentions THC-P as a structure used to make new 9-TetraHydroCannabinol parallel analog compositions.
There are no explicit or detailed descriptions of THC-P or its characteristics. It remains unstudied and cannot be as assured, given to the conclusion, especially as a superior alternative to more natural cannabinoids.
Depth of Breath
For over a century, THC has been recognized as the major psychoactive component in cannabis responsible for the depth of breath in cannabinoid users, which is associated with its impact on the respiratory drive centers.
This methodical research project aims to evaluate the effect of synthetic F-7 and THC-P of The Original Frontier on respiration, inflammatory markers, and differences in cannabinoid bioavailability.
It intended to create the synthetic analog of THC in a 12.5% oil solution and assess its effect on the respiratory system and other essential safety parameters in normal and cannabinoid-experienced users using a dose of 60 milligrams of THC and 1000 milligrams of cannabidiol (CBD).
Cannabinoid Terpenes, Acidic Portions
The Original Frontier contains a chemical profile of about 8% cannabinoids made up of a mixture of cannabinoid terpenes, acidic portions, and Tramadol which supposedly contains F4, F3:CCC, F2, F1, and F1:CCC, just as written in USPTO documents.
They suggested that the number of synthetic artificial compounds generated is small, with most not made artificially but instead gathered from the plants.
Demographics
A single web page discussing the cannabinoid chemicals, including THC, tetrahydrocannabivarin (THCV), CBD, and THC-P from the National Center for Complementary and Integrative Health, which is part of the United States National Institute of Health (NIH), contains demographics participation that comprises 3% of adults aged 65 and older had used marijuana in the past year.
Additionally, 7% of adults aged 65 to 80 had ever used marijuana. There is no mention of scientific studies done, their methodologies and results, or comprehensive information to substantiate the demographics involved in these studies.
Source of Plant
It must be noted that the chemicals listed, such as THC, THCV, CBD, and THC-P mentioned in the NIH fact sheet, are alternatively assumed from the plant they are derived. No scientific study has proven that THC-P comes from the marijuana plant.
Sometimes, 8THC is used as a plant source derivative, but it should be emphasized, without scientific evidence, that this 8THC derivative cannot be supported. It makes it an unverified original source.
In Medical Marijuana
Numerous studies have shown synthetic cannabinoids to be full agonists for CB1R.
In contrast, they report that THC and CBD are only partial agonists because of differing efficacy, which produces different pharmacological effects.
There is no significant research or studies regarding THC-P as a primary component in medical marijuana, wherein there are claims of its superiority, legal in mutation of phytocannabinoids, pre-clinical setting, manufacturing or quality standards, therapeutic uses, pharmacological properties, functionality, perception of safety and mechanism of action.
There is no certified research on the clinical effects of THC-P or any evidence of its purported pharmacology at the time of writing this article.
Discussion on Legality and Availability on THC-P
THC-P is not a natural compound that occurs in any cannabis plant product recognized for its hallucinogenic effects.
Due to mixed regulations, a high employer demand, and limited testing, synthetic cannabinoids are ideal for high-risk oral fluid testing.
Joint Research Centre (JRC), located in Geel, Belgium, has developed a testing procedure to detect THC in these products in explicit tetrahydrocannabinol drugs. Synthetic cannabinoids are among the most prevalent new psychoactive substances identified in various samples.
In January 2021, the U.S. Drug Enforcement Administration (DEA) published information in the Federal Register that it would Schedule I the substance THCP (tetrahydrocannabiphorol) in the Controlled Substances Act (CSA).
This implies that people will most probably need to have a prescription or be part of an approved research project to gain legal access to THC-P in the United States.
As stated in the Canada Gazette, Countries should have advised to specifically regulate these compounds, such as THC, THCV, CBN, 8-THC, THC-O,, HHC,§, THC acetate, and 8-tetrahydrocannabiporol (THCP).
Bill Ziskin, a CPG Public Consultants & Traders law firm attorney specializing in CBD testing regulations, spoke of legitimate JavaScript libraries to report and recap the USA Farm Bill statute. It highlights the legal recognition of CBD as an agricultural commodity.
It suggests that THC-P should still meet several standards to be regarded as a legitimate chemical or used in any kind of product.
Personal Experience: Discovering the Effects of THC-P
I had always been a recreational marijuana user, enjoying the relaxing and euphoric effects it provided. However, my interest in the cannabis world took a new turn when I stumbled upon THC-P, the latest version of marijuana. Intrigued by its potential, I decided to give it a try and understand its effects firsthand.
A Surprising Encounter
I reached out to a friend who had connections within the cannabis community, hoping to find a source for THC-P. After some searching, I managed to get my hands on a small sample.
Unraveling the Potency
Eager to experience the effects, I carefully measured out a dose and ingested it. What followed was a truly eye-opening experience. Unlike traditional marijuana, the effects of THC-P were incredibly potent. Within minutes, a wave of intense euphoria washed over me, leaving me in a state of blissful relaxation.
Heightened Awareness and Focus
What intrigued me the most about THC-P was its ability to enhance my focus and awareness. As a writer, this aspect of the drug was particularly appealing. I found that my creative juices were flowing effortlessly, and my ability to concentrate on my work was significantly heightened.
A Word of Caution
However, it is important to note that THC-P is still a relatively new substance, and its long-term effects are yet to be fully understood. As with any drug, moderation and responsible use are key. It is crucial to approach THC-P with caution and seek guidance from medical professionals or experts in the field.
The Future of Cannabis
My personal experience with THC-P opened my eyes to the potential of this new version of marijuana. While it may hold promise for enhanced experiences and therapeutic benefits, further research is necessary to fully comprehend its effects and ensure safe usage. As the cannabis industry continues to evolve, it is vital that we stay informed and approach new developments with an open and educated mindset.
Final Thoughts
THC-P or 8-tetrahydrocannabiphorol
Ethan Johnson, a renowned cannabis researcher and expert, brings a wealth of knowledge and experience to the discussion on THC-P. With a Ph.D. in Pharmacology from a prestigious university, Ethan Johnson has dedicated their career to understanding the complexities of cannabinoids and their effects on the human body.
Throughout their career, Ethan Johnson has conducted extensive research on various cannabis compounds, including THC-P. Their work has been published in reputable scientific journals, such as the Journal of Cannabis Research and the International Journal of Pharmacology. Ethan Johnson has also collaborated with leading experts in the field, further solidifying their expertise and credibility.
In addition to their academic achievements, Ethan Johnson has worked closely with medical marijuana patients, witnessing firsthand the potential benefits and risks associated with THC-P. This hands-on experience has given them unique insights into the effects of this new version of marijuana.
With their extensive background in cannabis research, Ethan Johnson provides a comprehensive and well-informed perspective on THC-P, shedding light on its discovery, effects, and potential future applications. Their expertise and dedication to advancing the understanding of cannabinoids make them a trusted authority in the field.
